hunters syndrome การใช้

• Hunter syndrome is X-linked while Hurler syndrome is autosomal recessive.
• There are also clinical trials of Elmiron to treat Hunters Syndrome ( MPS II ).
• A medical example is a heterokaryon composed of nuclei from Hurler syndrome and Hunter syndrome.
• If a male has an abnormal copy of the IDS gene, he will develop Hunter syndrome.
• Hurler syndrome is often classified as a lysosomal storage disease, and is clinically related to Hunter Syndrome.
• In March 1990, Conway became an experimental bone marrow donor for Mark Stevenson, a 4-year-old with Hunter syndrome.
• The behavioral symptoms of Hunter syndrome generally precede neurodegeneration and often increase in severity until the mental handicaps become more pronounced.
• Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome.
• Because of all these reasons, bone marrow grafts or hematopoietic stem cell transplantation have seen a decrease in their application as Hunter syndrome treatment.
• The company was able to produce enzymes targeting Hunter syndrome, Fabry disease and Pompe disease with expression levels and activity that supported further preclinical development.
• Yes, it's the Holly Hunter syndrome again : Give an actress nothing to say and she's bound to impress with her facial expressions and body language.
• In contrast, others with Hunter syndrome develop severe mental impairment and have life expectancies of 15 years or less, often due to neurodegeneration or physical complications from the disease.
• In Hunter syndrome, GAG builds up in cells throughout the body due to a progressive, and life-limiting, even when diagnosed as the " mild " or " attenuated " form.
• Genzyme Corp . and Transkaryotic Therapies Inc ., two biotech companies, have ended a long-running dispute and joined forces to sell a treatment for the genetic disorder known as Hunter syndrome.
• Most of these disorders are autosomal recessively inherited such as Niemann-Pick disease, type C, however a few are X-linked recessively inherited, such as Fabry disease and Hunter syndrome ( MPS II ).
• She has contributed to articles on the management of mucopolysaccharidosis type II ( Hunter syndrome ) and assessment of neurodevelopment in lysosomal storage diseases and related disorders using standardized and validated tools.
• And some diseases caused by genes on the X-chromosome, among them hemophilia, Duchenne muscular dystrophy and Hunter syndrome, have been linked to advanced age not of a child's father but of his maternal grandfather.
• While this treatment alternative is able to improve or stop the progression of some of the so-called " physical " symptoms, it does not prevent the eventual cognitive regression that occurs in Hunter syndrome patients who are cognitively affected, although it may slow such regression early on.
• Currently BioMarin Pharmaceutical produces enzyme replacement therapies for MPS type I and VI . Aldurazyme is an enzymatic replacement therapy for alpha-L-iduronidase produced by BioMarin for use in Type I MPS . In July 2006, the United States Food and Drug Administration approved a synthetic version of I2S produced by Shire Pharmaceuticals Group, called Elaprase, as a treatment for MPS type II ( Hunter syndrome ).